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$41.40 nett — One-time video consultation
Pay this once to get your prescription approved, valid for the next 12 months.
$146 nett / 60-day supply of treatment (2 bottles, 30ml each)
Charged only after your doctor approves your prescription.
How to use
Use TXA Face Serum once daily in the morning, unless your doctor advises otherwise. Your doctor will confirm your dose during your consultation. Some women may be prescribed twice-daily use.
Apply TXA to your whole face rather than spot-treating. Melasma often has diffuse, less-defined borders, so treating only the areas you can see may leave a noticeable edge.
Don’t skip your SPF
Daily SPF 50 is an essential part of melasma treatment. UV and visible light can both worsen melasma, and sun exposure in Singapore occurs year-round.
For additional protection against visible light, choose a sunscreen containing iron oxides, which generally provides better visible-light protection than clear sunscreens.
When should you expect results?
Give the treatment around three months before deciding how well it is working. Clinical trials ran for 12 weeks, with measurable improvement beginning from around week four.
If you develop a reaction to TXA, stop using it and contact us.
Storage and shelf life
Each order contains two 30ml bottles, with each bottle providing roughly one month of treatment. Keep the second bottle sealed until you need it.
01. Book your video consultation ($41.40 nett). Your doctor will assess your suitability and approve your treatment plan.
02. Treatment arrives at your door in 3 days. Once the doctor approves your treatments, your order will be processed and the delivery will reach you in 3 working days. Delivery is free.
03. Automatic refills. TXA arrives every 60 days, sent automatically. No reordering, no repeat consultation between reviews. Pause, skip or cancel at any time.
Tranexamic Acid 5% Niacinamide 3% Serum
Tranexamic Acid, Niacinamide, Hyaluronic Acid, Phenoxyethanol, Aqua
Morning serum for melasma and stubborn pigmentation, including pigmentation affected by hormonal changes during menopause.
TXA Face Serum is a prescription serum for melasma and stubborn pigmentation. It combines tranexamic acid with niacinamide.
Melasma is an ongoing process that causes your skin to produce excess pigment. That is why ordinary brightening creams may not be enough.
Tranexamic acid helps turn down the signals that tell your skin to produce excess pigment, while niacinamide helps reduce the transfer of pigment into surrounding skin cells. Together, they target pigmentation at different stages of the process.
Two things tend to happen at the same time: years of accumulated sun exposure, and changing hormones.
Oestrogen can directly affect the cells that produce pigment. These cells respond to oestrogen, which can increase melanin production and the amount of pigment transferred into the surrounding skin.⁸ ⁹
This may help explain why melasma can become more unpredictable during perimenopause. Hormones do not simply decline. Oestrogen can rise and fall significantly before eventually settling at a lower level. Melasma that first appeared during pregnancy can resurface, and pigmentation that once faded within months may linger for much longer.
As skin becomes thinner and more sensitive, irritation can trigger more pigment production. A spot, scratch or overly aggressive treatment may therefore leave a mark that takes much longer to fade.
What women in midlife usually describe
Tranexamic acid is best known as a medicine used to reduce heavy bleeding. When used on the skin, it can also help treat pigmentation.
It works by turning down the signals that tell your skin to make excess pigment. This helps address one of the processes driving melasma, rather than simply treating the pigment after it has formed.¹
As the skin naturally renews itself, reducing this ongoing pigment production can also allow existing pigmentation to gradually fade. So tranexamic acid is not just about preventing new pigment. It can help existing pigmentation become lighter over time.
It may also help calm some of the inflammation and changes in tiny blood vessels that are seen in melasma. This may help improve both the brown patches and the redness that can sometimes come with them.¹
Topical tranexamic acid 5% has been studied for melasma over 12 weeks, including in direct comparisons with hydroquinone 4%, a long-established treatment for melasma.
Studies suggest that topical tranexamic acid can improve melasma to a similar extent to hydroquinone, while generally causing fewer skin reactions. A 2025 study of tranexamic acid 5% combined with niacinamide also found significant improvement in melasma over three months.² ³
You may start to see improvement from around four weeks, with results continuing to build over the following months.⁴
TXA Face Serum is suitable for all skin types, including sensitive skin, and can be used alongside your other skincare.
It can be used with Menopausal Hormone Therapy. Starting or changing hormone therapy can itself affect melasma, so tell your doctor what you are taking.
Before you start
Melasma is a chronic condition. It is managed rather than cured completely, and it can return with sun exposure, heat and hormonal change.
TXA Face Serum is a prescription product and is dispensed after a video consultation.
TXA Face Serum is prescribed for persistent pigmentation, particularly melasma and pigmentation influenced by hormones and sun exposure.
It may be suitable if you have:
Your doctor will assess your skin and medical history during your consultation and confirm whether TXA is suitable for you.
Pigment-producing cells respond to oestrogen, which may partly explain why pigmentation can become more noticeable or unpredictable as hormone levels fluctuate during perimenopause.⁷
Years of accumulated sun exposure also play a role, and skin can become more sensitive to irritation with age. This combination can make pigmentation harder to manage than it was earlier in life.
If you use HRT and notice a significant change in your pigmentation, let your doctor know. The evidence linking HRT with melasma remains limited, but hormonal changes may influence pigmentation in some women.
Possibly. Tranexamic acid has also been studied for post-inflammatory hyperpigmentation, although the evidence is stronger for melasma.¹
Often, yes. Melasma that develops during pregnancy may fade after delivery, but some pigmentation persists or returns later. TXA may help with persistent pigmentation.
No. Tell your doctor if you are pregnant, breastfeeding or trying to conceive. If your circumstances change while using TXA, stop and contact us.
Yes. Tranexamic acid is also used as an oral medicine to reduce heavy menstrual bleeding. When applied to the skin at 5%, it works locally on pathways involved in pigmentation.
No. Despite its name, tranexamic acid is not an exfoliating acid. It does not remove or peel the surface layer of your skin. Instead, it helps interrupt signals involved in melanin production and pigment transfer. This can reduce the formation and spread of excess pigmentation.²
Hydroquinone has been a standard treatment for melasma for many years and can be very effective. However, it can cause irritation and is generally used for limited treatment periods.
Studies comparing topical tranexamic acid 5% with hydroquinone 4% found similar improvements in melasma, with fewer skin reactions reported with tranexamic acid.³ ⁴
This makes topical tranexamic acid a useful alternative for women who cannot tolerate hydroquinone, or who want a treatment suitable for longer-term management.
The two act on pigment by different routes.
Tranexamic acid 5% interrupts the signalling that drives melanin production, and calms the vascular component.
Niacinamide 3% works further along the chain, reducing the transfer of pigment from melanocytes into surrounding skin cells, and supporting the skin barrier. Barrier support matters because melasma-prone skin produces more pigment when it is irritated, so keeping the formulation comfortable is part of how it works.
No. TXA is not an exfoliating treatment and does not typically cause peeling or increased sun sensitivity.
Some people may experience mild dryness, redness or tingling, particularly when starting treatment.
Usually, yes. TXA can be used alongside gentle skincare products, and niacinamide is already included in the formulation.
If your usual products contain strong exfoliating acids or other potentially irritating ingredients, check with your doctor before combining them.
Yes, a simple routine is:
You may start to notice improvement from around four weeks, with results continuing to build over the following months. Most studies assess results after around 12 weeks.⁶
We recommend giving it at least three months before deciding how well it is working.
Melasma is a chronic condition and can return, particularly with sun exposure and hormonal changes. Stopping treatment does not mean the pigmentation will definitely return, but ongoing sun protection is important to help maintain your results.
If you want to stop treatment, speak with your doctor first.
References
Your treatments arrive within 3 working days of each charge, to the address on your account. Delivery is within Singapore only.
Moving, or want it sent somewhere else? Message us on WhatsApp at least 2 working days before your next scheduled charge, so we can update it before your order is dispensed.
If nothing has arrived after 3 working days, contact us and we will trace it.
This treatment is supplied only after clinical review and a valid prescription. If our doctor assesses that the treatment is not clinically appropriate for you, we will not dispense it, and you will not be charged for the product.
Billing and repeat delivery By proceeding with the consultation, you authorise Taylor to charge your nominated card for each treatment delivery, every 60 days, until your prescription expires 12 months later or you cancel. We will email you before each charge. You may pause, skip or cancel at any time by dropping us a Whatsapp message here, provided you do so at least 2 working days before your next scheduled charge. After that point your order is already being prepared by our pharmacy, so that delivery will go ahead as planned. Any changes will apply to the following one.
Delivery Orders are delivered within 3 working days of each charge, to the delivery address registered on your account. Delivery is available within Singapore only. It is your responsibility to keep your delivery address current. Address changes must be notified at least 2 working days before your next scheduled charge. We are not responsible for orders delivered to an out-of-date address that was not updated in time.
Prescription validity Prescriptions are valid for twelve (12) months from the date of issue. Deliveries will stop automatically when your prescription expires. To resume, book your annual video consultation. We will remind you in advance.
Taylor reserves the right to update the information or fees associated with this product without prior notice.
By placing an order, you consent to Taylor's Terms and Conditions and Privacy Policy.
For safety and regulatory reasons, dispensed prescription medicines cannot be returned, exchanged or refunded once they have left our pharmacy. This includes change of mind, and it includes products that have not been opened. We seek your understanding for this.
We will refund or replace an order in the following scenarios:
Report any damaged or incorrect item within 3 days of delivery, with a photograph, and we will replace it at no cost.
Orders can be cancelled without charge at any point before dispensing. Once an order has been dispensed, it cannot be cancelled.
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