$41.40 nett — One-time video consultation
Pay this once to get your prescription approved, valid for the next 12 months.
$52 nett / 60-day supply of treatment (1 gel pump, 15g)
Charged only after your doctor approves your prescription.
ATRA is a night product. Use it once daily in the evening, unless your doctor directs otherwise.
Begin with two to three nights a week and build up as your skin tolerates it. Most women reach nightly use within four to six weeks. Some settle at three or four nights a week, and that is fine.
If your skin feels tight, apply your moisturiser first and the ATRA on top. A pea-sized amount covers the whole face.
Give it 3-6 months for the treatment to show visible changes in your face.
Storage and shelf life
Store at room temperature, away from direct sunlight and heat. Keep the pump closed. The airless pump protects the actives, so there is no need to decant the product.
Use within 6 months of receiving it. Do not share it with anyone else. It has been prescribed for you.
01. Book your video consultation ($41.40 nett). Your doctor will assess your suitability and approve your treatment plan.
02. Treatment arrives at your door in 3 days. Once the doctor approves your treatments, your order will be processed and the delivery will reach you in 3 working days. Delivery is free.
03. Automatic refills. ATRA arrives every 60 days, sent automatically. No reordering, no repeat consultation between reviews. Pause, skip or cancel at any time.
Tretinoin 0.025%, Niacinamide 3%
Tretinoin, Niacinamide, Aloe Vera Extract, Argan Oil, Safflower Oil, Isopropyl Myristate, Hydrogel, Cyclopentasiloxane, Butylated Hydroxytoluene, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Polysorbate 80, Propylene Glycol, Phenoxyethanol, Ethylhexylglycerin, Aqua
An anti-aging night cream that speeds up cell renewal, reduces the breakdown of collagen and encourages new collagen to form.
ATRA Face Cream is a prescription night cream for skin that has become less smooth, firm and even in tone. It combines tretinoin 0.025% with niacinamide 3%. Tretinoin is one of the best-studied ingredients for ageing skin, with decades of clinical research behind it. It works inside the skin to speed up cell renewal, support new collagen production and slow collagen breakdown.¹
Tretinoin is retinoic acid, the active form of vitamin A that skin cells can use directly. Over-the-counter retinol has to go through several conversion steps in the skin before it becomes retinoic acid, and much of its potency is lost along the way.
Tretinoin skips these steps and works directly on skin cells. It speeds up skin-cell renewal, stimulates the production of collagen and glycosaminoglycans (molecules that help keep skin firm, hydrated and plump), and helps reduce the activity of enzymes called matrix metalloproteinases, which break down collagen after UV exposure.²
The evidence is strong. A 2025 network meta-analysis of 23 randomised trials involving 3,905 people found that tretinoin significantly improved fine wrinkles and identified tretinoin and retinol among the most effective topical treatments for uneven pigmentation.³
As oestrogen levels fall during perimenopause and menopause, skin becomes thinner, drier and less elastic, with a gradual loss of collagen.⁴ Tretinoin helps target some of these changes by stimulating collagen production and supporting faster skin renewal.
Research specifically in menopausal skin is still developing. In one randomised split-face study of women taking systemic hormone therapy, 0.05% tretinoin produced greater improvements in dermal elasticity than glycolic acid after four weeks.⁵
With consistent use over several months, these changes can translate into smoother texture, softer fine lines and a more even skin tone.
We use tretinoin 0.025%, a clinically established concentration designed for effective, long-term use. In comparative studies, different tretinoin strengths produced similar cosmetic improvement, while irritation increases with concentration.¹ ⁶
The main challenge is retinisation, when skin may become dry, flaky or irritated as it adjusts. To improve tolerability, we pair tretinoin with 3% niacinamide, which supports the skin barrier and helps retain moisture.
The result is a formulation designed to make tretinoin easier to use consistently, with less downtime.
ATRA Face Cream is suitable for most skin types, including sensitive skin, with a slower start. It can be used alongside your other skincare.
Not suitable if you are pregnant, breastfeeding or trying to conceive. Tell your doctor if your plans change while you are using it.
Before you start
ATRA Face Cream is a prescription product and is dispensed after a video consultation.
It is prescribed for cellular changes driven by sun exposure and ageing: fine lines, rough or dull texture, uneven skin tone, and loss of firmness. It is ideal if standard over-the-counter retinol has stopped giving visible results or if you are looking for an active with robust clinical evidence behind it.
Tretinoin is pure retinoic acid, the direct, biologically active form of vitamin A that your cells recognise and utilise immediately. Over-the-counter retinol must undergo a two-step conversion process within the skin to become retinoic acid, losing potency along the way. That direct biological activity is why tretinoin works faster and requires a prescription.
Mild flaking, dryness, and temporary skin congestion can occur during the first 2 to 6 weeks as cellular turnover accelerates. Starting at two to three nights per week, applying to completely dry skin, and buffering with a moisturiser helps keep this adjustment period manageable.
Yes, but with care. Tretinoin helps accelerate cellular turnover and pigment clearance, but if it causes severe irritation, that localised inflammation can trigger rebound hyperpigmentation. Your doctor may advise starting at a lower frequency (two nights a week) or pairing it with TXA Face Serum to calm pigment pathways.
Avoid the eyelids themselves and the inner corners of the eyes. You can apply it along the orbital bone where fine lines often form. Neck and chest skin is thinner, has fewer oil glands, and is more easily irritated, so consult your doctor before applying it below the jawline.
No. Topical prescription retinoids must not be used during pregnancy or while breastfeeding. Stop using ATRA if you are actively trying to conceive, and notify your doctor if your circumstances change.
Stop using ATRA at least 5 to 7 days before facial waxing, threading, chemical peels, or laser treatments. Tretinoin thins the outer stratum corneum, which increases the risk of epidermal tearing or burns from hot wax and energy-based devices. You can resume 2 to 3 days after your procedure once the skin barrier is completely calm.
Clinical trials show that 0.025% tretinoin delivers long-term collagen synthesis and photo-ageing benefits comparable to higher strengths, but with significantly lower rates of irritation and barrier disruption. The strength that works best is the one you can tolerate consistently over several months.
Tretinoin is highly concentrated, and you only need a single pea-sized amount to cover the entire face. A 15g tube is formulated to provide a full 60-day supply at that daily dose. Using more product does not accelerate results and will only trigger unnecessary peeling.
Morning: TXA Face Serum or Vitamin C, followed by moisturiser and broad-spectrum SPF 50.
Evening: E3 Face Cream first, wait 2 minutes until dry to the touch, apply a pea-sized amount of ATRA, and finish with your night moisturiser.
Your doctor will guide you on the prescription treatments you need.
You can continue using your daily cleanser, hydrating serums, moisturisers, and sunscreen. Avoid using benzoyl peroxide at the same time, as it oxidises and degrades tretinoin. Pause strong exfoliating acids (glycolic, lactic, salicylic) and physical scrubs while your skin adjusts.
Yes. Tretinoin accelerates cell turnover and thins the outermost dead layer of the epidermis, leaving new skin cells more vulnerable to UV exposure. Daily application of broad-spectrum SPF 50 is an essential component of the treatment plan.
Improvements in skin texture, smoothness, and radiance are typically visible between 8 and 12 weeks. Deeper collagen remodelling, increased firmness, and the softening of fine lines develop steadily over 6 months of continuous use.
The cellular and structural improvements gained from tretinoin depend on ongoing maintenance. If you stop using ATRA, your epidermal turnover rate will gradually return to its baseline over several months.
References
Your treatments arrive within 3 working days of each charge, to the address on your account. Delivery is within Singapore only.
Moving, or want it sent somewhere else? Message us on WhatsApp at least 2 working days before your next scheduled charge, so we can update it before your order is dispensed.
If nothing has arrived after 3 working days, contact us and we will trace it.
This treatment is supplied only after clinical review and a valid prescription. If our doctor assesses that the treatment is not clinically appropriate for you, we will not dispense it, and you will not be charged for the product.
Billing and repeat delivery By proceeding with the consultation, you authorise Taylor to charge your nominated card for each treatment delivery, every 60 days, until your prescription expires 12 months later or you cancel. We will email you before each charge. You may pause, skip or cancel at any time by dropping us a Whatsapp message here, provided you do so at least 2 working days before your next scheduled charge. After that point your order is already being prepared by our pharmacy, so that delivery will go ahead as planned. Any changes will apply to the following one.
Delivery Orders are delivered within 3 working days of each charge, to the delivery address registered on your account. Delivery is available within Singapore only. It is your responsibility to keep your delivery address current. Address changes must be notified at least 2 working days before your next scheduled charge. We are not responsible for orders delivered to an out-of-date address that was not updated in time.
Prescription validity Prescriptions are valid for twelve (12) months from the date of issue. Deliveries will stop automatically when your prescription expires. To resume, book your annual video consultation. We will remind you in advance.
Taylor reserves the right to update the information or fees associated with this product without prior notice.
By placing an order, you consent to Taylor's Terms and Conditions and Privacy Policy.
For safety and regulatory reasons, dispensed prescription medicines cannot be returned, exchanged or refunded once they have left our pharmacy. This includes change of mind, and it includes products that have not been opened. We seek your understanding for this.
We will refund or replace an order in the following scenarios:
Report any damaged or incorrect item within 3 days of delivery, with a photograph, and we will replace it at no cost.
Orders can be cancelled without charge at any point before dispensing. Once an order has been dispensed, it cannot be cancelled.
.png)
